Journal: Biomedical Microdevices

Article Title: Fabrication and characterization of spin-coated multilayer surface-eroding implants for automated multi-pulse drug delivery

doi: 10.1007/s10544-026-00848-4

Figure Lengend Snippet: Characterization of film uniformity: solvent casting vs. spin coating. ( a ) average thickness of three cast films (C1, C2, C3) and three spun films (S1, S2, S3), each measured at 20 punched locations; the film is the independent fabrication replicate ( n = 3 films per method) and the 20 within-film measurements are technical replicates nested within it (Section ). Error bars represent the standard deviation of the 20 within-film measurements. ( b ) inter-film standard deviation of average thickness across the three films per method, reflecting batch-to-batch variability. ( c ) intra-film standard deviation of thickness measurements within each individual film, reflecting within-film uniformity. ( d ) AFM surface topography image of solvent-cast film. ( e ) AFM surface topography image of spun film. ( f ) confocal Raman homogeneity maps of cast and spun films, one film per fabrication method, showing the spatial distribution of the CAP/F-127 peak-height ratio across a 0.3 × 0.3 mm area subdivided into a 3 × 3 grid of equally spaced measurement points

Article Snippet: Compositional homogeneity of spun and cast CAPP films was assessed by confocal Raman spectroscopy (HORIBA XploRA Plus, HORIBA Scientific, Edison, NJ) on film surfaces to characterize polymer distribution across both fabrication methods.

Techniques: Solvent, Standard Deviation